On Monday, the U.S. Bishops’ Conference voiced grief over a mass shooting in Las Vegas, Nevada, which has been called the deadliest mass shooting in modern American history. “My heart and my prayers, and those of my brother bishops and all the members of the Church, go out to the victims of this tragedy and to the city of Las Vegas,” said Cardinal Daniel N. DiNardo of Galveston-Houston, president of the United States Conference of Catholic Bishops, in an Oct. 2 statement.

Calling for prayer and care for those suffering, DiNardo offered a traditional Catholic prayer for the dead and asked protection from God for those who are suffering. “In the end, the only response is to do good — for no matter what the darkness, it will never overcome the light,” the cardinal counseled.

DiNardo’s statements follow an Oct. 1 shooting during a concert at the three-day Route 91 Harvest festival in Las Vegas, Nevada. While details are still emerging, at least 50 people have died, and the Las Vegas Police Department reports that around 500 people have been hospitalized due to the shooting. The sold-out concert was on the Las Vegas Strip, and thousands came to see acts including as Eric Church, Sam Hunt and Jason Aldean.

The shooter has been identified as 64-year-old Las Vegas local Stephen Paddock. According to the Associate Press, Paddock shot and killed himself in his hotel room as police tried to enter the room. Police are still investigating whether Paddock acted alone or with the help of accomplices.